Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
| ▸ | MMP12 | P39900 | 3/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700753 | 0.87 | SRD5A2 (0.73) | SRD5A2ALOX5MRGPRX4KDM4EALDH1A1 | |
| SCHEMBL7005455 | 0.86 | SRD5A2 (0.59) | SRD5A2MMP12MMP1ALOX5KDM4E | |
| SCHEMBL7004252 | 0.85 | SRD5A2 (0.58) | SRD5A2MMP12MMP1MAOBKDM4E | |
| SCHEMBL914178 | 0.80 | SRD5A2 (0.54) | SRD5A2KDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL15099347 | 0.78 | KDM4E (0.49) | SRD5A2MMP12MMP1KDM4EALDH1A1 | |
| SCHEMBL700154 | 0.77 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL30310641 | 0.77 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL699482 | 0.77 | FLT3 (0.60) | KDM4EALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL914490 | 0.77 | KDM4E (0.54) | SRD5A2KDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL916058 | 0.77 | SRD5A2 (0.49) | SRD5A2KDM4EALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200439-B1 | 1,2-DIHYDRO-1-OXO-PARAZINO(1,2-A) INDOLE DERIVATIVES | NOVUSPHARMA SPA (IT) | 2003-06-25 | — | — | EP | disclosed |