Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.32 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.32 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.32 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.32 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555838 | 0.81 | ALDH1A1 (0.36) | HTR2CMEN1KMT2AKDM4ERECQL | |
| SCHEMBL7013161 | 0.78 | EIF4EBP1 (0.48) | MEN1KMT2AKDM4EGAAEIF4EBP1 | |
| SCHEMBL15558636 | 0.72 | KMT2A (0.56) | MEN1KMT2AKDM4ERECQLPOLM | |
| SCHEMBL28645467 | 0.69 | KMT2A (0.50) | MEN1KMT2AKDM4ERECQLPOLM | |
| SCHEMBL15547541 | 0.69 | POLM (0.53) | MEN1KMT2AKDM4ERECQLPOLM | |
| SCHEMBL15547734 | 0.68 | POLM (0.55) | MEN1KMT2AKDM4ERECQLPOLM | |
| SCHEMBL15547127 | 0.68 | POLM (0.55) | MEN1KMT2AKDM4ERECQLPOLM | |
| SCHEMBL15548618 | 0.68 | KMT2A (0.56) | MEN1KMT2AKDM4ERECQLPOLM | |
| SCHEMBL8124006 | 0.67 | ALDH1A1 (0.47) | MEN1KMT2AKDM4ERECQL | |
| SCHEMBL6858495 | 0.67 | EIF4EBP1 (0.49) | MEN1KMT2AKDM4EGAAEIF4EBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958296-B1 | HETEROCYCLIC COMPOUNDS PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED DISEASES | REDDYS LAB LTD DR (IN) | 2003-07-30 | — | — | EP | disclosed |
| EP-0958296-A1 | NOVEL HETEROCYCLIC COMPOUNDS PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED DISEASES | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-11-24 | — | — | EP | disclosed |
| WO-1997041097-A2 | NOVEL HETEROCYCLIC COMPOUNDS PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED DISEASES | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1997-11-06 | — | — | WO | disclosed |