Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4EBP1 | Q13541 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858495 | 0.89 | EIF4EBP1 (0.49) | EIF4EBP1TSHRGAAL3MBTL1HTR1A | |
| SCHEMBL6555761 | 0.82 | EIF4EBP1 (0.52) | EIF4EBP1TSHRGAAHTR1AHTR7 | |
| SCHEMBL6555789 | 0.81 | EIF4EBP1 (0.50) | EIF4EBP1TSHRHTR1AHTR7MAPT | |
| SCHEMBL7004272 | 0.78 | HTR2C (0.34) | EIF4EBP1GAAMEN1KMT2AKDM4E | |
| SCHEMBL6858494 | 0.75 | EIF4EBP1 (0.49) | EIF4EBP1TSHRGAAHTR1AHTR7 | |
| SCHEMBL6858499 | 0.73 | EIF4EBP1 (0.49) | EIF4EBP1TSHRHTR1AHTR7MAPT | |
| SCHEMBL6555851 | 0.72 | MAPT (0.47) | EIF4EBP1L3MBTL1HTR7MAPTALDH1A1 | |
| SCHEMBL15558636 | 0.71 | KMT2A (0.56) | MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6557890 | 0.71 | ALDH1A1 (0.44) | EIF4EBP1L3MBTL1MAPTALDH1A1HPGD | |
| SCHEMBL7797529 | 0.71 | EIF4EBP1 (0.49) | EIF4EBP1TSHRGAAHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958296-B1 | HETEROCYCLIC COMPOUNDS PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED DISEASES | REDDYS LAB LTD DR (IN) | 2003-07-30 | — | — | EP | disclosed |