SCHEMBL7004298

SCHEMBL7004298

CCCCCONC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6729067 0.97
SCHEMBL9816113 0.97 EPHX1 (0.46)
SCHEMBL13745905 0.97 EPHX1 (0.46)
SCHEMBL15283192 0.97 EPHX1 (0.46)
SCHEMBL15283021 0.97 EPHX1 (0.46)
SCHEMBL15282804 0.97 EPHX1 (0.46)
Bromide SCHEMBL29006840 0.95 EPHX1 (0.45)
SCHEMBL4769334 0.91
SCHEMBL13745196 0.84 LPAR2 (0.50)
SCHEMBL8044051 0.79 THRB (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6080857-A CONTACTING AN AMINE NUCLEOPHILE WITH AN A,B-UNSATURATED AMIDE DERIVATIVE SUCH AS ACYL UREA, OR CARBOXYLIC IMIDE IN THE PRESENCE OF A CHIRAL LEWIS ACID COMPLEX OF A CHIRAL BISOXAZOLINYLMETHANE WITH AN AZOPHILIC METACATION SALT NORTH DAKOTA STATE UNIVERSITY (US) 2000-06-27 US claimed
EP-1315733-A2 METHOD FOR PRODUCING ANELLATED TETRAHYDRO-[1H]-TRIAZOLES BASF AKTIENGESELLSCHAFT (DE) 2003-06-04 EP disclosed
US-6472408-B1 TWO 5- AMINO-5,6,7,8-TETRAHYDROQUINOLINE FRAGMENTS JOINED TOGETHER BY A DIVALENT LINKING GROUP; CHOLINESTERASE INHIBITORS THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) 2002-10-29 US disclosed
WO-2002020531-A2 METHOD FOR PRODUCING ANELLATED TETRAHYDRO-[1H]-TRIAZOLES BASF AKTIENGESELLSCHAFT (DE) 2002-03-14 WO disclosed
US-6191283-B1 Pyrazole intermediates in a method of preparation of β-amino acids NDSU-RESEARCH FOUNDATION 2001-02-20 US disclosed
US-6080857-A CONTACTING AN AMINE NUCLEOPHILE WITH AN A,B-UNSATURATED AMIDE DERIVATIVE SUCH AS ACYL UREA, OR CARBOXYLIC IMIDE IN THE PRESENCE OF A CHIRAL LEWIS ACID COMPLEX OF A CHIRAL BISOXAZOLINYLMETHANE WITH AN AZOPHILIC METACATION SALT NORTH DAKOTA STATE UNIVERSITY (US) 2000-06-27 US disclosed