⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004298 | 0.91 | — | — | |
| SCHEMBL9816113 | 0.88 | EPHX1 (0.46) | — | |
| SCHEMBL15283021 | 0.88 | EPHX1 (0.46) | — | |
| SCHEMBL13745905 | 0.88 | EPHX1 (0.46) | — | |
| SCHEMBL15282804 | 0.88 | EPHX1 (0.46) | — | |
| SCHEMBL6729067 | 0.88 | — | — | |
| SCHEMBL15283192 | 0.88 | EPHX1 (0.46) | — | |
| Bromide SCHEMBL29006840 | 0.86 | EPHX1 (0.45) | — | |
| SCHEMBL2606460 | 0.80 | — | — | |
| SCHEMBL2340182 | 0.78 | ADRB2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9399735-B2 | Mannich-base inhibitor for decalcification, preparation method and application thereof | PETROCHINA COMPANY LIMITED (CN) | 2016-07-26 | — | — | US | claimed |
| US-20130256602-A1 | MANNICH-BASE INHIBITOR FOR DECALCIFICATION, PREPARATION METHOD AND APPLICATION THEREOF | PETROCHINA COMPANY LIMITED (CN) | 2013-10-03 | — | — | US | claimed |
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | Asteroid Therapeutics | 2023-10-26 | — | — | US | disclosed |
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | Asteroid Therapeutics | 2023-10-26 | — | — | US | disclosed |
| CN-110831997-B | Mixtures of radically curable compounds and their use | 喜利得股份公司 | 2022-02-22 | — | — | CN | disclosed |
| EP-3892272-A1 | BIFUNCTIONAL MOLECULES FOR DEGRADATION OF EGFR AND METHODS OF USE | Dana-Farber Cancer Institute, Inc. (US) | 2021-10-13 | — | — | EP | disclosed |
| EP-3307258-B1 | ARYL SULFONOHYDRAZIDES | UNIV MONASH (AU) | 2020-12-16 | — | — | EP | disclosed |
| CN-105452398-B | Composition for ink, ink jet recording method and tingle body using this composition for ink | 日本化药株式会社 | 2018-07-10 | — | — | CN | disclosed |
| EP-2770977-B1 | NOVEL DOSAGE FORM | NEUROVIVE PHARMACEUTICAL AB (SE) | 2017-07-12 | — | — | EP | disclosed |
| US-9504728-B2 | Dosage form | NEUROVIVE PHARMACEUTICAL AB (SE) | 2016-11-29 | — | — | US | disclosed |
| US-9504728-B2 | Dosage form | NEUROVIVE PHARMACEUTICAL AB (SE) | 2016-11-29 | — | — | US | disclosed |
| US-4863954-A | Acyloxythiophene-carboxamide fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| EP-0207355-B1 | ALKOXYCARBONYL-SUBSTITUTED HYDROXYTHIOPHENE CARBOXAMIDES | BAYER AG (DE) | 1988-10-19 | — | — | EP | disclosed |
| US-4767757-A | Acyloxythiophene-carboxamide fungicides, compositions and use | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-30 | — | — | US | disclosed |
| US-4752607-A | Alkoxycarbonyl-substituted hydroxythiophene-carboxamides, fungicidal compositions and use | BAYER AKTIENGESELLSCHAFT (DE) | 1988-06-21 | — | — | US | disclosed |
| EP-0260827-A2 | Coating compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-23 | — | — | EP | disclosed |
| EP-0241735-A2 | Acyloxythiophene carbon amide | BAYER AG (DE) | 1987-10-21 | — | — | EP | disclosed |
| EP-0207355-A1 | Alkoxycarbonyl-substituted hydroxythiophene carboxamides | BAYER AG (DE) | 1987-01-07 | — | — | EP | disclosed |
| US-4322271-A | ETHERIFICATION OF AN N-ETHYL AMIDE BY ANODIZING WITH AN ALCOHOL; ALKYLATION; DEETHERIFICATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-03-30 | — | — | US | disclosed |
| US-4288300-A | IN ELECTROLYTIC CELL HAVING ALKALI METAL OR TETRAALKYLAMMONIUM ALKOSULFATE AS ELECTROLYTE | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-08 | — | — | US | disclosed |