Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.71 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7009286 | 0.83 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL7238295 | 0.83 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL7010711 | 0.77 | MTNR1A (0.51) | MTNR1AMTNR1BHPGD | |
| SCHEMBL7094962 | 0.77 | MAPT (0.56) | MTNR1AMTNR1BHPGD | |
| Ammonia Solution, Strong SCHEMBL27509223 | 0.75 | MAPT (0.55) | MTNR1AMTNR1BHPGD | |
| SCHEMBL7007379 | 0.75 | MTNR1A (0.65) | MTNR1AMTNR1B | |
| SCHEMBL7004821 | 0.75 | MTNR1A (0.65) | MTNR1AMTNR1B | |
| SCHEMBL7009066 | 0.73 | MTNR1A (0.76) | MTNR1AMTNR1B | |
| SCHEMBL7237873 | 0.73 | MTNR1A (0.76) | MTNR1AMTNR1B | |
| SCHEMBL29496815 | 0.72 | MTNR1A (0.49) | MTNR1AMTNR1BALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583319-B1 | Treating or preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-06-24 | — | — | US | disclosed |
| EP-0994102-B1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | disclosed |
| EP-0994102-A1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-04-19 | — | — | EP | disclosed |