Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 6/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7238295 | 1.00 | MTNR1A (1.00) | MTNR1AMTNR1BSMN1; SMN2NPSR1KDM1A | |
| SCHEMBL7009066 | 0.86 | MTNR1A (0.76) | MTNR1AMTNR1BKDM1AMAOA | |
| SCHEMBL7237873 | 0.86 | MTNR1A (0.76) | MTNR1AMTNR1BKDM1AMAOA | |
| SCHEMBL7238675 | 0.85 | MTNR1B (0.74) | MTNR1AMTNR1BKDM1AMAOA | |
| SCHEMBL7005394 | 0.85 | MTNR1B (0.74) | MTNR1AMTNR1BKDM1AMAOA | |
| SCHEMBL7006478 | 0.85 | MTNR1A (1.00) | MTNR1AMTNR1BSMN1; SMN2NPSR1 | |
| SCHEMBL7230881 | 0.85 | MTNR1A (1.00) | MTNR1AMTNR1BSMN1; SMN2NPSR1 | |
| SCHEMBL7004392 | 0.83 | MTNR1A (0.71) | MTNR1AMTNR1B | |
| SCHEMBL7007379 | 0.79 | MTNR1A (0.65) | MTNR1AMTNR1B | |
| SCHEMBL7004821 | 0.79 | MTNR1A (0.65) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583319-B1 | Treating or preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-06-24 | — | — | US | claimed |
| EP-0994102-B1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | claimed |
| EP-0994102-A1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-04-19 | — | — | EP | claimed |
| US-6583319-B1 | Treating or preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-06-24 | — | — | US | disclosed |
| EP-0994102-B1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | disclosed |
| EP-0994102-A1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-04-19 | — | — | EP | disclosed |