Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879138 | 0.87 | CHEK1 (0.50) | TDP1NOS1MAPTPARP1NPC1 | |
| SCHEMBL6007713 | 0.87 | TDP1 (0.52) | TDP1NOS1MAPTPARP1NPC1 | |
| SCHEMBL28907048 | 0.81 | MAPT (0.57) | TDP1NOS1MAPTPARP1NPC1 | |
| SCHEMBL29478497 | 0.81 | MAPT (0.57) | TDP1NOS1MAPTPARP1NPC1 | |
| SCHEMBL6009063 | 0.77 | TSHR (0.55) | TDP1NOS1MAPTPARP1NPC1 | |
| SCHEMBL9055483 | 0.75 | GRIN2D (0.53) | TDP1NOS1MAPTPARP1CDK2 | |
| SCHEMBL3433685 | 0.75 | TDP1 (0.53) | TDP1NOS1MAPTPARP1NPC1 | |
| SCHEMBL1799350 | 0.74 | TYMS (0.47) | TDP1NOS1MAPTPARP1L3MBTL1 | |
| SCHEMBL3915197 | 0.74 | L3MBTL1 (0.57) | TDP1NOS1MAPTPARP1NPC1 | |
| SCHEMBL31326011 | 0.74 | L3MBTL1 (0.57) | TDP1NOS1MAPTPARP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1327632-A1 | METHOD FOR PRODUCING TRIMER OF INDOLE DERIVATIVE, AND TRIMER OF INDOLE DERIVATIVE AND LAMINATED STRUCTURE THEREOF | Mitsubishi Rayon Co., Ltd. (JP) | 2003-07-16 | — | — | EP | disclosed |