Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 18/20 | 0.80 |
| ▸ | MMP13 | P45452 | 18/20 | 0.80 |
| ▸ | MMP2 | P08253 | 2/20 | 0.80 |
| ▸ | MMP3 | P08254 | 2/20 | 0.80 |
| ▸ | MMP9 | P14780 | 2/20 | 0.80 |
| ▸ | MMP8 | P22894 | 2/20 | 0.80 |
| ▸ | MMP12 | P39900 | 1/20 | 0.55 |
| ▸ | MMP14 | P50281 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4048453 | 1.00 | MMP1 (0.80) | MMP1MMP13MMP2MMP3MMP9 | |
| Hydroxyamine SCHEMBL19181460 | 0.98 | MMP1 (0.77) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6996574 | 0.89 | MMP1 (1.00) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6994719 | 0.89 | MMP1 (1.00) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6994722 | 0.89 | MMP1 (1.00) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL3855639 | 0.88 | MMP1 (0.76) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7886290 | 0.86 | MMP1 (0.62) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6998188 | 0.85 | MMP1 (0.71) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6998192 | 0.85 | MMP1 (0.71) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6872351 | 0.84 | MMP1 (0.67) | MMP1MMP13MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070069-B1 | BICYCLIC HYDROXAMIC ACID DERIVATIVES | PFIZER PROD INC (US) | 2003-07-16 | — | — | EP | disclosed |
| EP-1070069-A1 | BICYCLIC HYDROXAMIC ACID DERIVATIVES | Pfizer Products Inc. (US) | 2001-01-24 | — | — | EP | disclosed |
| US-6110964-A | FOR TREATING ARTHRITIS, INFLAMMATORY BOWEL DISEASE, CROHN'S DISEASE, EMPHYSEMA, ACUTE RESPIRATORY DISTRESS SYNDROME, ASTHMA CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ALZHEIMER'S DISEASE, ORGAN TRANSPLANT TOXICITY, CACHEXIA, CANCER | PFIZER INC. (US) | 2000-08-29 | — | — | US | disclosed |
| WO-1999052910-A1 | BICYCLIC HYDROXAMIC ACID DERIVATIVES | PFIZER PRODUCTS INC. (US) | 1999-10-21 | — | — | WO | disclosed |