Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 17/20 | 0.62 |
| ▸ | MMP13 | P45452 | 17/20 | 0.62 |
| ▸ | MMP2 | P08253 | 3/20 | 0.59 |
| ▸ | MMP9 | P14780 | 3/20 | 0.59 |
| ▸ | MMP3 | P08254 | 2/20 | 0.59 |
| ▸ | MMP8 | P22894 | 2/20 | 0.59 |
| ▸ | MMP12 | P39900 | 1/20 | 0.57 |
| ▸ | MMP14 | P50281 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27415619 | 0.87 | MMP1 (0.76) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL7004525 | 0.86 | MMP1 (0.80) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL4048453 | 0.86 | MMP1 (0.80) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL6869740 | 0.85 | MMP1 (0.77) | MMP1MMP13MMP2MMP9MMP3 | |
| Hydroxyamine SCHEMBL19181460 | 0.84 | MMP1 (0.77) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL7134741 | 0.84 | MMP1 (0.56) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL7886196 | 0.84 | MMP1 (0.56) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL27448685 | 0.84 | MMP1 (0.64) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL2575324 | 0.81 | MMP1 (0.79) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL1080224 | 0.80 | MMP1 (0.80) | MMP1MMP13MMP2MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214870-B1 | ANTIARTHRITIC AGENTS; ANTICANCER AGENTS | PFIZER INC | 2001-04-10 | — | — | US | disclosed |