Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094863 | 1.00 | ADORA1 (0.40) | ADORA1MAPTKDM4EALDH1A1RAD52 | |
| SCHEMBL7094861 | 1.00 | ADORA1 (0.40) | ADORA1MAPTKDM4EALDH1A1RAD52 | |
| SCHEMBL5770549 | 0.90 | ADORA1 (0.38) | ADORA1MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL5770553 | 0.90 | ADORA1 (0.38) | ADORA1MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL5771598 | 0.90 | ADORA1 (0.38) | ADORA1MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL7211154 | 0.90 | ADORA1 (0.38) | ADORA1MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL6049947 | 0.82 | ADORA1 (0.44) | ADORA1MAPTKDM4EALDH1A1RAD52 | |
| SCHEMBL6049924 | 0.81 | ADORA1 (0.33) | ADORA1ALDH1A1KMT2AMEN1 | |
| SCHEMBL6049921 | 0.81 | ADORA1 (0.33) | ADORA1ALDH1A1KMT2AMEN1 | |
| SCHEMBL7003545 | 0.78 | KEAP1 (0.40) | ADORA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301516-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2003-04-16 | — | — | EP | disclosed |