Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31061623 | 0.84 | NPC1 (1.00) | NPC1MTOR | |
| SCHEMBL338729 | 0.84 | NPC1 (1.00) | NPC1MTOR | |
| SCHEMBL29532115 | 0.84 | NPC1 (1.00) | NPC1MTOR | |
| SCHEMBL22476146 | 0.78 | ALDH1A1 (0.48) | NPC1MTOR | |
| SCHEMBL339249 | 0.68 | NPC1 (0.65) | NPC1MTOR | |
| SCHEMBL338691 | 0.68 | NPC1 (0.71) | NPC1MTOR | |
| SCHEMBL339136 | 0.66 | NPC1 (0.68) | NPC1MTOR | |
| SCHEMBL9709367 | 0.65 | NPC1 (0.54) | NPC1MTOR | |
| SCHEMBL25282379 | 0.64 | NPC1 (0.67) | NPC1MTOR | |
| SCHEMBL29411871 | 0.64 | NPC1 (0.67) | NPC1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322615-A2 | FLUORINATED QUINOLONES AS ANTIMITOTIC AND ANTITUMOR AGENTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2003-07-02 | — | — | EP | disclosed |
| US-6569870-B1 | Anticarcinogenic agents for breast and ovarian cancer | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2003-05-27 | — | — | US | disclosed |
| WO-2002026730-A2 | FLUORINATED QUINOLONES AS ANTIMITOTIC AND ANTITUMOR AGENTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2002-04-04 | — | — | WO | disclosed |