Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709265 | 0.78 | GAA (0.58) | NPC1MTOR | |
| SCHEMBL4219929 | 0.74 | ALDH1A1 (0.61) | NPC1 | |
| SCHEMBL338729 | 0.70 | NPC1 (1.00) | NPC1MTOR | |
| SCHEMBL29532115 | 0.70 | NPC1 (1.00) | NPC1MTOR | |
| SCHEMBL31061623 | 0.70 | NPC1 (1.00) | NPC1MTOR | |
| SCHEMBL21479878 | 0.69 | MAPK10 (0.45) | NPC1MTOR | |
| SCHEMBL20346767 | 0.69 | PDE5A (0.41) | NPC1MTOR | |
| SCHEMBL20346681 | 0.68 | PDE5A (0.41) | NPC1MTOR | |
| SCHEMBL15918659 | 0.67 | KDM4E (0.47) | NPC1MTOR | |
| SCHEMBL12836459 | 0.67 | FEN1 (0.52) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471516-A1 | Tricyclic heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-19 | — | — | EP | disclosed |