Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.31 |
| ▸ | ORAI2 | Q96SN7 | 2/20 | 0.31 |
| ▸ | ORAI3 | Q9BRQ5 | 2/20 | 0.31 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15906658 | 0.80 | TRPV6 (0.48) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| SCHEMBL25718172 | 0.66 | — | — | |
| SCHEMBL14140296 | 0.66 | — | — | |
| SCHEMBL125450 | 0.65 | TRPV6 (0.53) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| SCHEMBL24284446 | 0.62 | GAA (0.31) | — | |
| SCHEMBL3807753 | 0.62 | ALDH1A1 (0.36) | — | |
| SCHEMBL991201 | 0.62 | TRPV6 (0.50) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| SCHEMBL11103898 | 0.62 | TRPV6 (0.50) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| Fluoride SCHEMBL5958527 | 0.62 | TRPV6 (0.50) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| SCHEMBL3887343 | 0.62 | TRPV6 (0.50) | ORAI1ORAI2ORAI3TRPV6CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012062655-A2 | PHOTOPOLYMER FORMULATION FOR PRODUCING HOLOGRAPHIC MEDIA HAVING HIGHLY CROSS-LINKED MATRIX POLYMERS | BAYER MATERIALSCIENCE AG (DE) | 2012-05-18 | — | — | WO | disclosed |