SCHEMBL700537

SCHEMBL700537

Fc1cccc(C=Cc2cccc(F)c2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 11/20 1.00
PTGS1 P23219 3/20 0.72
PTGS2 P35354 1/20 0.72
NQO2 P16083 1/20 0.69
RELA Q04206 1/20 0.64
CYP1A2 P05177 1/20 0.62
CYP3A4 P08684 1/20 0.62
CYP2D6 P10635 1/20 0.62
PKM P14618 1/20 0.62
MAPK1 P28482 1/20 0.62
THPO P40225 1/20 0.62
NPC1 O15118 1/20 0.62
CHRM5 P08912 1/20 0.62
GRM5 P41594 1/20 0.62
RAB9A P51151 1/20 0.62
BLM P54132 1/20 0.62
PMP22 Q01453 1/20 0.62
FBP1 P09467 1/20 0.61
GRM4 Q14833 1/20 0.55
MAOA P21397 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL700536 1.00 NFE2L2 (1.00) NFE2L2PTGS1PTGS2NQO2RELA
SCHEMBL31317689 1.00 NFE2L2 (1.00) NFE2L2PTGS1PTGS2NQO2RELA
SCHEMBL9849735 0.95 NFE2L2 (0.91) NFE2L2PTGS1PTGS2NQO2RELA
SCHEMBL700304 0.93 NFE2L2 (1.00) NFE2L2PTGS1PTGS2NQO2RELA
SCHEMBL700305 0.93 NFE2L2 (1.00) NFE2L2PTGS1PTGS2NQO2RELA
SCHEMBL29446272 0.93 NFE2L2 (1.00) NFE2L2PTGS1PTGS2NQO2RELA
SCHEMBL14401249 0.93 NFE2L2 (1.00) NFE2L2PTGS1PTGS2NQO2RELA
SCHEMBL698583 0.91 NFE2L2 (1.00) NFE2L2PTGS1PTGS2NQO2RELA
SCHEMBL698584 0.91 NFE2L2 (1.00) NFE2L2PTGS1PTGS2NQO2RELA
SCHEMBL9849728 0.89 NFE2L2 (0.78) NFE2L2PTGS1PTGS2NQO2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8703388-B2 Optical data storage media GENERAL ELECTRIC COMPANY (US) 2014-04-22 US disclosed
US-8507153-B2 Compositions, optical data storage media and methods for using the optical data storage media GENERAL ELECTRIC COMPANY (US) 2013-08-13 US disclosed
EP-2423917-B1 Use of chemically bonded dyes in holographic data storage media GEN ELECTRIC (US) 2013-08-07 EP disclosed
US-8343608-B2 Use of appended dyes in optical data storage media GENERAL ELECTRIC COMPANY (US) 2013-01-01 US disclosed
EP-2290651-B1 Compositions, optical data storage media and methods for using the optical data storage media GEN ELECTRIC (US) 2012-10-10 EP disclosed
EP-2290408-B1 Compositions, optical data storage media and methods for using the optical data storage media GEN ELECTRIC (US) 2012-08-15 EP disclosed
US-20120163145-A1 OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2012-06-28 US disclosed
US-20120052232-A1 USE OF APPENDED DYES IN OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2012-03-01 US disclosed
EP-2423917-A2 Use of chemically bonded dyes in holographic data storage media General Electric Company (US) 2012-02-29 EP disclosed
US-8124299-B2 Methods for using optical data storage media GENERAL ELECTRIC COMPANY (US) 2012-02-28 US disclosed
US-20110053054-A1 COMPOSITIONS, OPTICAL DATA STORAGE MEDIA AND METHODS FOR USING THE OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2011-03-03 US disclosed
US-20110053055-A1 COMPOSITIONS, OPTICAL DATA STORAGE MEDIA AND METHODS FOR USING THE OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2011-03-03 US disclosed
EP-2290408-A1 Compositions, optical data storage media and methods for using the optical data storage media General Electric Company (US) 2011-03-02 EP disclosed
EP-2290651-A1 Compositions, optical data storage media and methods for using the optical data storage media General Electric Company (US) 2011-03-02 EP disclosed
US-20100302927-A1 OPTICAL DATA STORAGE MEDIUM AND METHODS FOR USING THE SAME GENERAL ELECTRIC COMPANY (US) 2010-12-02 US disclosed