Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 14/20 | 1.00 |
| ▸ | RELA | Q04206 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.66 |
| ▸ | NQO2 | P16083 | 1/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698583 | 1.00 | NFE2L2 (1.00) | NFE2L2RELAPTGS1NQO2PTGS2 | |
| SCHEMBL9849735 | 0.95 | NFE2L2 (0.91) | NFE2L2RELAPTGS1NQO2PTGS2 | |
| SCHEMBL700537 | 0.91 | NFE2L2 (1.00) | NFE2L2RELAPTGS1NQO2PTGS2 | |
| SCHEMBL31317689 | 0.91 | NFE2L2 (1.00) | NFE2L2RELAPTGS1NQO2PTGS2 | |
| SCHEMBL700536 | 0.91 | NFE2L2 (1.00) | NFE2L2RELAPTGS1NQO2PTGS2 | |
| SCHEMBL29446272 | 0.88 | NFE2L2 (1.00) | NFE2L2RELAPTGS1NQO2PTGS2 | |
| SCHEMBL14401249 | 0.88 | NFE2L2 (1.00) | NFE2L2RELAPTGS1NQO2PTGS2 | |
| SCHEMBL700304 | 0.88 | NFE2L2 (1.00) | NFE2L2RELAPTGS1NQO2PTGS2 | |
| SCHEMBL700305 | 0.88 | NFE2L2 (1.00) | NFE2L2RELAPTGS1NQO2PTGS2 | |
| SCHEMBL3366024 | 0.85 | NFE2L2 (0.74) | NFE2L2RELAPTGS1NQO2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2810198-B1 | ANTI-INVASIVE COMPOUNDS | UNIV GENT (BE) | 2023-07-12 | — | — | EP | disclosed |
| US-9290427-B2 | Anti-invasive compounds | UNIVERSITEIT GENT (BE) | 2016-03-22 | — | — | US | disclosed |
| US-20150011620-A1 | ANTI-INVASIVE COMPOUNDS | UNIVERSITEIT GENT (BE) | 2015-01-08 | — | — | US | disclosed |
| EP-2810198-A1 | ANTI-INVASIVE COMPOUNDS | Universiteit Gent (BE) | 2014-12-10 | — | — | EP | disclosed |
| US-8703388-B2 | Optical data storage media | GENERAL ELECTRIC COMPANY (US) | 2014-04-22 | — | — | US | disclosed |
| US-8507153-B2 | Compositions, optical data storage media and methods for using the optical data storage media | GENERAL ELECTRIC COMPANY (US) | 2013-08-13 | — | — | US | disclosed |
| WO-2013113722-A1 | ANTI-INVASIVE COMPOUNDS | UNIVERSITEIT GENT (BE) | 2013-08-08 | — | — | WO | disclosed |
| EP-2423917-B1 | Use of chemically bonded dyes in holographic data storage media | GEN ELECTRIC (US) | 2013-08-07 | — | — | EP | disclosed |
| US-8343608-B2 | Use of appended dyes in optical data storage media | GENERAL ELECTRIC COMPANY (US) | 2013-01-01 | — | — | US | disclosed |
| EP-2290651-B1 | Compositions, optical data storage media and methods for using the optical data storage media | GEN ELECTRIC (US) | 2012-10-10 | — | — | EP | disclosed |
| EP-2290408-B1 | Compositions, optical data storage media and methods for using the optical data storage media | GEN ELECTRIC (US) | 2012-08-15 | — | — | EP | disclosed |
| US-20120163145-A1 | OPTICAL DATA STORAGE MEDIA | GENERAL ELECTRIC COMPANY (US) | 2012-06-28 | — | — | US | disclosed |
| US-20120052232-A1 | USE OF APPENDED DYES IN OPTICAL DATA STORAGE MEDIA | GENERAL ELECTRIC COMPANY (US) | 2012-03-01 | — | — | US | disclosed |
| EP-2423917-A2 | Use of chemically bonded dyes in holographic data storage media | General Electric Company (US) | 2012-02-29 | — | — | EP | disclosed |
| US-8124299-B2 | Methods for using optical data storage media | GENERAL ELECTRIC COMPANY (US) | 2012-02-28 | — | — | US | disclosed |
| US-20110053054-A1 | COMPOSITIONS, OPTICAL DATA STORAGE MEDIA AND METHODS FOR USING THE OPTICAL DATA STORAGE MEDIA | GENERAL ELECTRIC COMPANY (US) | 2011-03-03 | — | — | US | disclosed |
| US-20110053055-A1 | COMPOSITIONS, OPTICAL DATA STORAGE MEDIA AND METHODS FOR USING THE OPTICAL DATA STORAGE MEDIA | GENERAL ELECTRIC COMPANY (US) | 2011-03-03 | — | — | US | disclosed |
| EP-2290408-A1 | Compositions, optical data storage media and methods for using the optical data storage media | General Electric Company (US) | 2011-03-02 | — | — | EP | disclosed |
| EP-2290651-A1 | Compositions, optical data storage media and methods for using the optical data storage media | General Electric Company (US) | 2011-03-02 | — | — | EP | disclosed |
| US-20100302927-A1 | OPTICAL DATA STORAGE MEDIUM AND METHODS FOR USING THE SAME | GENERAL ELECTRIC COMPANY (US) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011620-A1 | ANTI-INVASIVE COMPOUNDS | MMP3, MMP10, MIF | NFE2L2 1215/4885RELA 402/4885PTGS1 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.