Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6623288 | 0.78 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL14422893 | 0.74 | HTR1B (0.52) | ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL30740922 | 0.71 | HTR1B (0.46) | HTR1ACHRNB2CHRNA4 | |
| SCHEMBL5422564 | 0.70 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL14562245 | 0.67 | MTNR1A (0.59) | ALDH1A1 | |
| SCHEMBL11548891 | 0.66 | DRD4 (0.66) | — | |
| SCHEMBL4280446 | 0.66 | NPC1 (0.46) | ALDH1A1 | |
| SCHEMBL18265853 | 0.66 | HDAC8 (0.35) | — | |
| SCHEMBL5859016 | 0.66 | TAAR1 (0.46) | — | |
| SCHEMBL15547011 | 0.66 | HDAC8 (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289994-A1 | PROCESS FOR THE PREPARATION OF 2-AMINO-5,8-DIMETHOXY 1,2,4]TRIAZOLO 1,5-c]PYRIMIDINE | Dow AgroSciences LLC (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001098305-A1 | PROCESS FOR THE PREPARATION OF 2-AMINO-5,8-DIMETHOXY[1,2,4]TRIAZOLO[1,5-c]PYRIMIDINE | DOW AGROSCIENCES LLC (US) | 2001-12-27 | — | — | WO | disclosed |