Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 6/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11836199 | 0.74 | ADRA1A (0.42) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| SCHEMBL6847058 | 0.74 | ADRA1A (0.42) | ADRA1AADRA1DOPRK1 | |
| Hydrochloric Acid SCHEMBL3453049 | 0.73 | ADRA1A (0.41) | ADRA1AADRA1DOPRK1 | |
| Hydrochloric Acid SCHEMBL1844678 | 0.71 | ADRA1A (0.41) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| SCHEMBL13531413 | 0.71 | HTR3A (0.42) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| SCHEMBL7332677 | 0.71 | HTR3A (0.39) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL9049059 | 0.70 | HTR3A (0.39) | ADRA1AADRA1DHTR3AADRA2AADRA2B | |
| SCHEMBL20972935 | 0.69 | — | — | |
| SCHEMBL20972936 | 0.69 | — | — | |
| SCHEMBL6850928 | 0.69 | HTR3A (0.38) | ADRA1AADRA1DHTR3AADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268484-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001068652-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2001-09-20 | — | — | WO | disclosed |