SCHEMBL7006466

SCHEMBL7006466

COC(=O)C(C#N)=CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14345886 1.00
SCHEMBL10783575 1.00
SCHEMBL7009020 0.98 ADORA2A (0.45)
SCHEMBL7618854 0.85
SCHEMBL7474650 0.85
SCHEMBL18655709 0.85
SCHEMBL11653074 0.79 ADORA2A (0.41)
SCHEMBL2132134 0.79
SCHEMBL2132138 0.79
SCHEMBL5555667 0.79 ADORA2A (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1054859-A4 PROCESSES AND INTERMEDIATES USEFUL TO MAKE ANTIFOLATES LILLY CO ELI (US) 2003-03-05 EP disclosed
US-6426417-B1 CYCLIZATION OF A CYANO-ESTER DERIVATIVE WITH 2,6-DIAMINO-6-HYDROXYPYRIMIDINE IN THE PRESENCE OF ACETIC ACID AND ACETONITRILE ELI LILLY AND COMPANY 2002-07-30 US disclosed
EP-1213609-A2 High contrast thermally-developable imaging materials containing barrier layer EASTMAN KODAK COMPANY (US) 2002-06-12 EP disclosed
US-6352819-B1 MATERIAL COMPRISING SUPPORT, THERMALLY-DEVELOPABLE IMAGING LAYER COMPRISING BINDER, PHOTOSENSITIVE SILVER HALIDE, SOURCE OF REDUCIBLE SILVER IONS, REDUCING AGENT AND HIGH CONTRAST AGENT, AND BARRIER LAYER COMPRISING FILM FORMING POLYMER EASTMAN KODAK COMPANY 2002-03-05 US disclosed
EP-1054859-A1 PROCESSES AND INTERMEDIATES USEFUL TO MAKE ANTIFOLATES ELI LILLY AND COMPANY (US) 2000-11-29 EP disclosed
WO-1999041230-A1 PROCESSES AND INTERMEDIATES USEFUL TO MAKE ANTIFOLATES ELI LILLY AND COMPANY (US) 1999-08-19 WO disclosed
US-4665218-A Method for the preparation of alkoxymethylene compounds of acetic esters and substituted acetic esters DYNAMIT NOBEL AG (DE) 1987-05-12 US disclosed