SCHEMBL5555667

SCHEMBL5555667

COC=C(C#N)C(=O)OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.41
ADORA2B P29275 1/20 0.41
ADORA1 P30542 1/20 0.41
POLB P06746 1/20 0.40
APP P05067 2/20 0.39
KDM4E B2RXH2 7/20 0.38
ALDH1A1 P00352 5/20 0.37
KMT2A Q03164 4/20 0.37
MAPT P10636 3/20 0.37
LMNA P02545 2/20 0.37
TNNI3 P19429 1/20 0.37
CRHBP P24387 1/20 0.37
TNNT2 P45379 1/20 0.37
KLK7 P49862 1/20 0.37
TNNC1 P63316 1/20 0.37
CRHR2 Q13324 1/20 0.37
CYP2C9 P11712 1/20 0.36
MEN1 O00255 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11653074 1.00 ADORA2A (0.41) ADORA2AADORA2BADORA1POLBAPP
SCHEMBL7618854 0.83
SCHEMBL7474650 0.83
SCHEMBL18655709 0.83
SCHEMBL667301 0.79 ALDH1A1 (0.46) KDM4EALDH1A1KMT2AMAPTLMNA
SCHEMBL2671868 0.79 CYP2C9 (0.43) ADORA2AADORA2BADORA1POLBAPP
SCHEMBL2671866 0.79 CYP2C9 (0.43) ADORA2AADORA2BADORA1POLBAPP
SCHEMBL11653026 0.79 ALDH1A1 (0.46) KDM4EALDH1A1KMT2AMAPTLMNA
SCHEMBL31636860 0.79 CYP2C9 (0.61) POLBKDM4EALDH1A1KMT2AMAPT
SCHEMBL28549047 0.79 CYP1A2 (0.34) KDM4EALDH1A1CYP2C9NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10471174-B2 Cyanoacrylate medical adhesive and preparation method and use thereof Shen, Wei (CN) 2019-11-12 US claimed
EP-3335738-B1 NEW TYPE CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF SHEN WEI (CN) 2019-11-06 EP claimed
US-20190175782-A1 NOVEL CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF SHEN, WEI (CN) 2019-06-13 US claimed
EP-3335738-A1 NEW TYPE CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF Shen, Wei (CN) 2018-06-20 EP claimed
US-4933220-A Using cyanoacrylate ARMSTRONG WORLD INDUSTRIES, INC. (US) 1990-06-12 US claimed
CN-115215767-B Process for preparing 2-cyano-3-ethoxyacrylic acid ethyl ester derivative 帕潘纳(北京)科技有限公司 2023-09-12 CN disclosed
CN-115215767-A Process for preparing 2-cyano-3-ethoxy ethyl acrylate derivatives 帕潘纳(北京)科技有限公司 2022-10-21 CN disclosed
US-10471174-B2 Cyanoacrylate medical adhesive and preparation method and use thereof Shen, Wei (CN) 2019-11-12 US disclosed
EP-3335738-B1 NEW TYPE CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF SHEN WEI (CN) 2019-11-06 EP disclosed
US-20190175782-A1 NOVEL CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF SHEN, WEI (CN) 2019-06-13 US disclosed
EP-3335738-A1 NEW TYPE CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF Shen, Wei (CN) 2018-06-20 EP disclosed
US-20160264587-A1 Compounds Useful for Inhibiting Metastasis from Cancer and Methods Using Same UNIV DREXEL (US) 2016-09-15 US disclosed
US-6977278-B1 Cyanoacrylate compositions curable to flexible polymeric materials LOCTITE (R&D) LTD. (IE) 2005-12-20 US disclosed
EP-1360257-A1 CYANOACRYLATE COMPOSITIONS CURABLE TO FLEXIBLE POLYMERIC MATERIALS Loctite (R & D) Limited (IE) 2003-11-12 EP disclosed
WO-2002053666-A1 CYANOACRYLATE COMPOSITIONS CURABLE TO FLEXIBLE POLYMERIC MATERIALS LOCTITE (R & D) LIMITED (IE) 2002-07-11 WO disclosed
US-4987232-A ONE POT, GOOD YIELD SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ, B.V. (NL) 1991-01-22 US disclosed
EP-0372654-A2 Preparation of 2-chloropyridine 3-carboxylic acid esters SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-06-13 EP disclosed
US-4665218-A Method for the preparation of alkoxymethylene compounds of acetic esters and substituted acetic esters DYNAMIT NOBEL AG (DE) 1987-05-12 US disclosed
US-4559342-A Quinolone acids and antibacterial agents containing these compounds BAYER AKTIENGESELLSCHAFT (DE) 1985-12-17 US disclosed
US-4104049-A Chlorine-substituted vinylaminobenzoic acid compounds and plant growth regulant compositions BAYER AKTIENGESELLSCHAFT (DE) 1978-08-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160264587-A1 Compounds Useful for Inhibiting Metastasis from Cancer and Methods Using Same CX3CR1, CCL2, CCR5 ADORA2A 302/4885ADORA2B 839/4885ADORA1 368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.