Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 17/20 | 0.52 |
| ▸ | ITGB6 | P18564 | 6/20 | 0.50 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.50 |
| ▸ | ITGB8 | P26012 | 2/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008295 | 0.85 | ITGB3 (0.70) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL7008303 | 0.85 | ITGB3 (0.70) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL7009188 | 0.82 | ITGB3 (0.57) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL7009184 | 0.82 | ITGB3 (0.57) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL7448376 | 0.77 | ITGB3 (0.60) | ITGAVITGB3ITGB5ITGA2B | |
| SCHEMBL7375986 | 0.77 | ITGB3 (0.60) | ITGAVITGB3ITGB5ITGA2B | |
| SCHEMBL7920986 | 0.77 | ITGB3 (0.60) | ITGAVITGB3ITGB5ITGA2B | |
| SCHEMBL7375994 | 0.77 | ITGB3 (0.60) | ITGAVITGB3ITGB5ITGA2B | |
| SCHEMBL7549076 | 0.76 | ITGB3 (0.74) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL20481251 | 0.76 | ITGAV (0.52) | ITGAVITGB3ITGB6ITGB5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946165-B1 | INTEGRIN ANTAGONISTS | MERCK & CO INC (US) | 2003-04-09 | — | — | EP | claimed |