Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.60 |
| ▸ | ITGAV | P06756 | 20/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.53 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448376 | 1.00 | ITGB3 (0.60) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7375994 | 1.00 | ITGB3 (0.60) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7920986 | 1.00 | ITGB3 (0.60) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7405861 | 0.87 | ITGB3 (0.77) | ITGB3ITGAVITGA2B | |
| SCHEMBL7373202 | 0.87 | ITGB3 (0.77) | ITGB3ITGAVITGA2B | |
| SCHEMBL7373207 | 0.87 | ITGB3 (0.77) | ITGB3ITGAVITGA2B | |
| SCHEMBL7373199 | 0.87 | ITGB3 (0.77) | ITGB3ITGAVITGA2B | |
| SCHEMBL7405865 | 0.87 | ITGB3 (0.77) | ITGB3ITGAVITGA2B | |
| SCHEMBL7006493 | 0.77 | ITGAV (0.52) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7924358 | 0.76 | ITGB3 (0.79) | ITGB3ITGAVITGA2BITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998046220-A1 | COMBINATION THERAPY FOR THE PREVENTION AND TREATMENT OF OSTEOPOROSIS | MERCK & CO., INC. (US) | 1998-10-22 | — | — | WO | disclosed |