Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 7/20 | 0.33 |
| ▸ | F10 | P00742 | 6/20 | 0.33 |
| ▸ | F2 | P00734 | 4/20 | 0.33 |
| ▸ | F7 | P08709 | 2/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.31 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.31 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014454 | 0.96 | F10 (0.34) | PRSS1F10F2F7PLG | |
| SCHEMBL7008407 | 0.90 | F10 (0.38) | PRSS1F10F2F7PLG | |
| SCHEMBL7008013 | 0.89 | F10 (0.39) | PRSS1F10F2EGLN1NAMPT | |
| SCHEMBL7006080 | 0.89 | ITGB3 (0.39) | PRSS1F10F2F7PLG | |
| SCHEMBL7006800 | 0.87 | RXFP1 (0.35) | F10F2NAMPTST14 | |
| SCHEMBL7009371 | 0.86 | F10 (0.39) | F10F2F7PLGF3 | |
| SCHEMBL7011271 | 0.86 | F10 (0.40) | F10F2 | |
| SCHEMBL7011604 | 0.79 | F10 (0.41) | PRSS1F10F2F7PLG | |
| SCHEMBL7006078 | 0.78 | F2 (0.41) | F10F2F7PLGF3 | |
| SCHEMBL7013669 | 0.77 | F10 (0.38) | F10F2F7PLGF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614664-B2 | Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-01-08 | — | — | EP | claimed |
| EP-0614664-B1 | Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-09-16 | — | — | EP | claimed |