Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.39 |
| ▸ | KLK1 | P06870 | 3/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006800 | 0.92 | RXFP1 (0.35) | F10ITGB3ITGA2BMAPTRXFP1 | |
| SCHEMBL7008013 | 0.91 | F10 (0.39) | F10ITGB3ITGA2BMAPTRXFP1 | |
| SCHEMBL7008119 | 0.90 | F10 (0.45) | F10KLKB1KLK1TPSAB1F2 | |
| SCHEMBL7006080 | 0.87 | ITGB3 (0.39) | F10KLK1ITGB3ITGA2BF2 | |
| SCHEMBL7014454 | 0.87 | F10 (0.34) | F10MAPK8ITGB3ITGA2BF2 | |
| SCHEMBL7006567 | 0.86 | PRSS1 (0.33) | F10F2 | |
| SCHEMBL7013669 | 0.82 | F10 (0.38) | F10F2 | |
| SCHEMBL7011604 | 0.81 | F10 (0.41) | F10F2 | |
| SCHEMBL7011265 | 0.79 | ITGB3 (0.39) | ITGB3ITGA2BMAPT | |
| SCHEMBL7009371 | 0.77 | F10 (0.39) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614664-B2 | Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-01-08 | — | — | EP | claimed |
| EP-0614664-B1 | Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-09-16 | — | — | EP | claimed |