Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TYMS | P04818 | 9/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8141944 | 0.88 | TYMS (0.43) | LMNAALDH1A1THRBTSHRMAPK1 | |
| SCHEMBL8005983 | 0.83 | NPC1 (0.45) | LMNAALDH1A1THRBTSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL7013906 | 0.80 | TYMS (0.42) | LMNAALDH1A1THRBTSHRMAPK1 | |
| SCHEMBL8089394 | 0.79 | CYP1A2 (0.32) | ALDH1A1GAA | |
| SCHEMBL8409771 | 0.79 | TYMS (0.46) | LMNAALDH1A1THRBTSHRMAPK1 | |
| SCHEMBL8409818 | 0.79 | LMNA (0.49) | LMNAALDH1A1THRBTSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL7672774 | 0.78 | LMNA (0.48) | LMNAALDH1A1THRBTSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL7672979 | 0.78 | TYMS (0.45) | LMNAALDH1A1THRBTSHRMAPK1 | |
| SCHEMBL8410247 | 0.77 | NPC1 (0.43) | LMNAALDH1A1MAPK1TYMSSMN1; SMN2 | |
| SCHEMBL8413272 | 0.77 | NPC1 (0.43) | LMNAALDH1A1MAPK1TYMSSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772593-B1 | THIOPYRIDYL COMPOUNDS FOR CONTROLLING HELICOBACTER BACTERIA | ALTANA PHARMA AG (DE) | 2003-05-02 | — | — | EP | disclosed |
| US-6162809-A | Pyridylthio compounds for controlling helicobacter bacteria | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-12-19 | — | — | US | disclosed |