Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 11/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7672979 | 0.97 | TYMS (0.45) | TYMSLMNAALDH1A1THRBTSHR | |
| SCHEMBL8409818 | 0.90 | LMNA (0.49) | TYMSLMNAALDH1A1THRBTSHR | |
| Hydrochloric Acid SCHEMBL7672774 | 0.88 | LMNA (0.48) | TYMSLMNAALDH1A1THRBTSHR | |
| Hydrochloric Acid SCHEMBL7013906 | 0.84 | TYMS (0.42) | TYMSLMNAALDH1A1THRBTSHR | |
| SCHEMBL6871145 | 0.82 | TYMS (0.40) | TYMSLMNAALDH1A1THRBTSHR | |
| SCHEMBL6865756 | 0.81 | TYMS (0.41) | TYMSLMNAALDH1A1THRBTSHR | |
| SCHEMBL8410247 | 0.80 | NPC1 (0.43) | TYMSLMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL7676058 | 0.80 | KDR (0.42) | TYMSLMNAALDH1A1THRBTSHR | |
| SCHEMBL6862014 | 0.80 | TYMS (0.40) | TYMSLMNAALDH1A1THRBTSHR | |
| SCHEMBL7006898 | 0.79 | LMNA (0.44) | TYMSLMNAALDH1A1THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859030-A | Substituted arylalkylthioalkylthiopyridines for use in the control of helicobacter bacteria | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-01-12 | — | — | US | disclosed |
| EP-0764161-A1 | SUBSTITUTED ARYLALKYLTHIOALKYLTHIOPYRIDINES FOR USE IN THE CONTROL OF HELICOBACTER BACTERIA | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1997-03-26 | — | — | EP | disclosed |
| WO-1995034554-A1 | SUBSTITUTED ARYLALKYLTHIOALKYLTHIOPYRIDINES FOR USE IN THE CONTROL OF HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1995-12-21 | — | — | WO | disclosed |