Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18609120 | 0.91 | ESR1 (0.57) | ESR1ESR2OPRM1TAAR1SLC6A2 | |
| SCHEMBL4056401 | 0.87 | SIGMAR1 (0.46) | OPRM1TAAR1SLC6A2ADRA1ASIGMAR1 | |
| Bicarbonate SCHEMBL28105724 | 0.84 | EPHX1 (0.49) | KMT2A | |
| SCHEMBL14137752 | 0.82 | SOAT1 (0.44) | TAAR1SLC6A2SIGMAR1 | |
| SCHEMBL14119146 | 0.78 | SLC7A5 (0.48) | ESR1ESR2TAAR1SIGMAR1MEN1 | |
| SCHEMBL983099 | 0.77 | SLC6A2 (0.55) | ESR1ESR2TAAR1SLC6A2MEN1 | |
| SCHEMBL28131612 | 0.76 | SIGMAR1 (0.48) | SIGMAR1 | |
| SCHEMBL4602654 | 0.76 | ESR1 (0.81) | ESR1ESR2OPRM1TAAR1SLC6A2 | |
| SCHEMBL1936402 | 0.76 | ESR1 (0.81) | ESR1ESR2OPRM1TAAR1SLC6A2 | |
| SCHEMBL1840026 | 0.75 | TAAR1 (0.57) | ESR1ESR2TAAR1SLC6A2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1267906-A1 | LACTAMS AS INHIBITORS OF A-BETA PROTEIN PRODUCTION | Bristol-Myers Squibb Pharma Company (US) | 2003-01-02 | — | — | EP | claimed |
| WO-2001072324-A1 | LACTAMS AS INHIBITORS OF A-BETA PROTEIN PRODUCTION | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-10-04 | — | — | WO | claimed |