Sugi Predict

Sugi Predict / Compounds / SCHEMBL7007271

SCHEMBL7007271

SCHEMBL7007271

CCOC(=O)CN(CCCCCCNc1nsc2nccn12)S(=O)(=O)c1cccc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ F13A1 P00488 10/20 0.56
▸ TGM1 P22735 4/20 0.49
▸ NR1D1 P20393 1/20 0.38
▸ TSHR P16473 2/20 0.36
▸ GAA P10253 1/20 0.36
▸ TOP2A P11388 1/20 0.35
▸ POLB P06746 1/20 0.34
▸ RAD52 P43351 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ UHRF1 Q96T88 1/20 0.34
▸ CNR2 P34972 1/20 0.34
▸ HDAC3 O15379 1/20 0.33
▸ HDAC1 Q13547 1/20 0.33
▸ HDAC2 Q92769 1/20 0.33
▸ HDAC6 Q9UBN7 1/20 0.33
▸ NCOR2 Q9Y618 1/20 0.33
▸ HTR2A P28223 1/20 0.33
▸ HTR2C P28335 1/20 0.33
▸ HTR7 P34969 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7004053 0.94 F13A1 (0.54) F13A1TGM1TOP2AKMT2A
SCHEMBL7008472 0.89 F13A1 (0.57) F13A1TGM1HDAC3HDAC1HDAC2
SCHEMBL7007196 0.89 F13A1 (0.54) F13A1TGM1HTR2AHTR2CHTR7
SCHEMBL7080074 0.86 F13A1 (0.59) F13A1TGM1HTR2AHTR2CHTR7
SCHEMBL7005996 0.85 F13A1 (0.54) F13A1TGM1HTR2AHTR2CHTR7
SCHEMBL7004876 0.85 F13A1 (0.56) F13A1TGM1KMT2AHTR2AHTR2C
SCHEMBL7007005 0.79 F13A1 (0.75) F13A1TGM1HTR2AHTR7
SCHEMBL7010746 0.77 F13A1 (0.48) F13A1TGM1GAA
SCHEMBL7005895 0.77 F13A1 (0.48) F13A1TGM1KMT2A
SCHEMBL7004052 0.76 F13A1 (0.56) F13A1TGM1TOP2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030225007-A1 Sulfonamide derivatives of 3-substituted imidazol[1,2-d]-1,2,4-thiadiazoles and 3-substituted-[1,2,4] thiadiazolo[4,5-a] benzimidazole as inhibitors of fibrin cross-linking and transglutaminases APOTEX INC. 2003-12-04 — — US claimed
EP-1348710-A1 Sulfonamide derivatives of 3-substituted imidazo[1,2-D]-1,2,4-thiadiazoles and 3-substituted-[1,2,4]thiadiazolo[4,5-A]benzimidazole as inhibitors of fibrin cross-linking and transglutaminases Apotex Inc. (CA) 2003-10-01 — — EP claimed
US-20030225007-A1 Sulfonamide derivatives of 3-substituted imidazol[1,2-d]-1,2,4-thiadiazoles and 3-substituted-[1,2,4] thiadiazolo[4,5-a] benzimidazole as inhibitors of fibrin cross-linking and transglutaminases APOTEX INC. 2003-12-04 — — US disclosed
EP-1348710-A1 Sulfonamide derivatives of 3-substituted imidazo[1,2-D]-1,2,4-thiadiazoles and 3-substituted-[1,2,4]thiadiazolo[4,5-A]benzimidazole as inhibitors of fibrin cross-linking and transglutaminases Apotex Inc. (CA) 2003-10-01 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030225007-A1 Sulfonamide derivatives of 3-substituted imidazol[1,2-d]-1,2,4-thiadiazoles and 3-substituted-[1,2,4] thiadiazolo[4,5-a] benzimidazole as inhibitors of fibrin cross-linking and transglutaminases PIGS, FGB, SERPINE1 F13A1 14/4885TGM1 7/4885NR1D1 2966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.