Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 8/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.44 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7230872 | 1.00 | HTR2A (0.55) | HTR2AHTR2CHTR2BKDM1AMAOA | |
| SCHEMBL7228652 | 0.77 | MTNR1A (0.43) | HTR2AHTR2CHTR2BKDM1AMTNR1A | |
| SCHEMBL7011548 | 0.77 | MTNR1A (0.43) | HTR2AHTR2CHTR2BKDM1AMTNR1A | |
| SCHEMBL7007406 | 0.74 | MTNR1A (0.51) | MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL7007411 | 0.74 | MTNR1A (0.51) | MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL7012028 | 0.73 | MTNR1A (0.52) | MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL7012026 | 0.73 | MTNR1A (0.52) | MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL7012397 | 0.72 | MTNR1A (0.61) | HTR2AHTR2CHTR2BKDM1AMAOA | |
| SCHEMBL7236200 | 0.72 | MTNR1A (0.61) | HTR2AHTR2CHTR2BKDM1AMAOA | |
| SCHEMBL23287803 | 0.71 | MTNR1A (0.48) | MTNR1AMTNR1BBACE1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583319-B1 | Treating or preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-06-24 | — | — | US | disclosed |
| EP-0994102-B1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | disclosed |
| EP-0994102-A1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-04-19 | — | — | EP | disclosed |