Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 5/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011548 | 1.00 | MTNR1A (0.43) | MTNR1ASLC6A4KDM1AHTR5ACYP2A6 | |
| SCHEMBL7014782 | 0.89 | MTNR1A (0.41) | MTNR1ASLC6A4KDM1AHTR5ACYP2A6 | |
| SCHEMBL7006204 | 0.86 | MTNR1A (0.40) | MTNR1ASLC6A4HTR5ACYP2A6DRD2 | |
| SCHEMBL7237119 | 0.81 | MTNR1A (0.40) | MTNR1ASLC6A4CYP2A6 | |
| SCHEMBL7237123 | 0.81 | MTNR1A (0.40) | MTNR1ASLC6A4CYP2A6 | |
| SCHEMBL7010863 | 0.80 | MTNR1A (0.46) | MTNR1ASLC6A4HTR5ACYP2A6DRD2 | |
| SCHEMBL7007293 | 0.77 | HTR2A (0.55) | MTNR1ASLC6A4KDM1ANPC1RAB9A | |
| SCHEMBL7230872 | 0.77 | HTR2A (0.55) | MTNR1ASLC6A4KDM1ANPC1RAB9A | |
| SCHEMBL8820684 | 0.74 | MTNR1A (0.41) | MTNR1ASLC6A4DRD2HTR2C | |
| SCHEMBL10224643 | 0.74 | MTNR1A (0.62) | MTNR1AHTR5ACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583319-B1 | Treating or preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-06-24 | — | — | US | disclosed |