Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12349572 | 0.75 | ALDH1A1 (0.83) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL6295225 | 0.71 | ALDH1A1 (0.91) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL6804691 | 0.71 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL6701095 | 0.71 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL6703572 | 0.71 | KDM4E (0.54) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL6804689 | 0.71 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL6703570 | 0.71 | KDM4E (0.54) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL7009691 | 0.69 | MAPT (0.55) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL6705511 | 0.69 | MAPT (0.76) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL6999361 | 0.69 | MAPT (1.00) | ALDH1A1MAPTLMNAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150964-B1 | POLYCYCLIC PYRIMIDINE-2,4(1H, 3H)-DIONE WITH FUNCTIONALIZED ALKYL RADICALS IN 1- AND/OR 3-POSITION, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS | IBFB GMBH PRIVATES INST FUER B (DE) | 2003-10-29 | — | — | EP | disclosed |