Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.83 |
| ▸ | MAPT | P10636 | 6/20 | 0.83 |
| ▸ | LMNA | P02545 | 1/20 | 0.83 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | CFTR | P13569 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.53 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6295225 | 0.89 | ALDH1A1 (0.91) | ALDH1A1MAPTLMNACYP1A2KDM4E | |
| SCHEMBL8121950 | 0.78 | MAPT (0.53) | ALDH1A1MAPTLMNACYP2C19CYP1A2 | |
| SCHEMBL839648 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNACYP2C19CYP1A2 | |
| SCHEMBL7007301 | 0.75 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNACYP1A2KDM4E | |
| SCHEMBL8120744 | 0.75 | GRM1 (0.51) | ALDH1A1MAPTLMNAALOX15HPGD | |
| Hydrochloric Acid SCHEMBL11675656 | 0.75 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNACYP2C19CYP1A2 | |
| SCHEMBL6299773 | 0.74 | ALDH1A1 (0.67) | ALDH1A1MAPTLMNACYP2C19CYP1A2 | |
| SCHEMBL23578376 | 0.73 | MAPT (0.62) | ALDH1A1MAPTLMNACYP2C19CYP1A2 | |
| SCHEMBL9533570 | 0.73 | ALDH1A1 (0.59) | ALDH1A1MAPTLMNACYP1A2GAA | |
| SCHEMBL8124560 | 0.72 | MAPK1 (0.54) | ALDH1A1MAPTLMNACYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450333-B2 | Molecules for regulating cell death | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-05-28 | — | — | US | disclosed |
| US-8450333-B2 | Molecules for regulating cell death | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-05-28 | — | — | US | disclosed |
| US-7994182-B2 | Quinazolinone-derivatives and their use for preparation of pharmaceutical compositions having PARP enzyme inhibitory effect | PECSI TUDOMANYEGYETEM (HU) | 2011-08-09 | — | — | US | disclosed |
| EP-1622881-B1 | QUINAZOLINONE-DERIVATIVES AND THEIR USE FOR PREPARATION OF PHARMACEUTICAL COMPOSITIONS HAVING PARP ENZYME INHIBITORY EFFECT | PECSI TUDOMANYEGYETEM (HU) | 2010-05-26 | — | — | EP | disclosed |
| US-20080287473-A1 | NOVEL MOLECULES FOR REGULATING CELL DEATH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080287473-A1 | NOVEL MOLECULES FOR REGULATING CELL DEATH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-11-20 | — | — | US | disclosed |
| US-20070042935-A1 | Quinazolinone-derivatives and their use for preparation of pharmaceutical compositions having parp enzyme inhibitory effect | PECSI TUDOMANYEGYETEM (HU) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287473-A1 | NOVEL MOLECULES FOR REGULATING CELL DEATH | AIFM1, BAX, HSPE1 | ALDH1A1 4015/4885MAPT 3063/4885LMNA 1467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.