Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004219 | 0.94 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTPOLBNPC1 | |
| SCHEMBL7008108 | 0.94 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTPOLBNPC1 | |
| SCHEMBL7010822 | 0.94 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTPOLBNPC1 | |
| SCHEMBL7012340 | 0.90 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTPOLBNPC1 | |
| SCHEMBL7004200 | 0.86 | TOP1 (0.48) | ALDH1A1LMNAMAPTPOLBKDM4E | |
| SCHEMBL7004278 | 0.85 | STAT3 (0.43) | ALDH1A1LMNAMAPTPOLBNPC1 | |
| SCHEMBL7004246 | 0.84 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTPOLBNPC1 | |
| SCHEMBL7010630 | 0.84 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTPOLBNPC1 | |
| SCHEMBL7012840 | 0.84 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTPOLBNPC1 | |
| SCHEMBL7008195 | 0.84 | STAT3 (0.52) | ALDH1A1LMNAMAPTPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787720-B1 | PYRIDONECARBOXYLATE DERIVATIVE OR SALT THEREOF AND ANTIBACTERIAL CONTAINING THE SAME AS ACTIVE INGREDIENT | WAKUNAGA SEIYAKU KK (JP) | 2003-07-16 | — | — | EP | disclosed |
| US-5910498-A | NOVEL COMPOUNDS HAVING REDUCED CYTOTOXICITY, PHOTOTOXICITY; TREATING BACTERIAL AND VIRAL INFECTIONS | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0787720-A1 | NOVEL PYRIDONECARBOXYLATE DERIVATIVE OR SALT THEREOF AND ANTIBACTERIAL CONTAINING THE SAME AS ACTIVE INGREDIENT | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-06 | — | — | EP | disclosed |