Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2206337 | 0.74 | CCR1 (0.50) | PRKCIMEN1KMT2AHSP90AA1KDM4E | |
| SCHEMBL28083103 | 0.70 | KDM4E (0.41) | PRKCIAXLMEN1KMT2AHSP90AA1 | |
| SCHEMBL3577754 | 0.70 | AXL (0.47) | PRKCIAXL | |
| SCHEMBL20296322 | 0.68 | MAPK1 (0.35) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL31509775 | 0.68 | LMNA (0.48) | MEN1KMT2AHSP90AA1KDM4EAPAF1 | |
| SCHEMBL112474 | 0.68 | LMNA (0.48) | MEN1KMT2AHSP90AA1KDM4EAPAF1 | |
| SCHEMBL29191973 | 0.67 | AXL (0.36) | AXL | |
| SCHEMBL25323059 | 0.67 | AXL (0.48) | AXLMEN1KMT2AHSP90AA1APAF1 | |
| SCHEMBL30551090 | 0.67 | AXL (0.48) | AXLMEN1KMT2AHSP90AA1APAF1 | |
| SCHEMBL1463005 | 0.67 | PDE4A (0.35) | KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1075478-B1 | PHENYLUREA AND PHENYLTHIO UREA DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2003-04-16 | — | — | EP | claimed |