Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4391353 | 0.84 | FAAH (0.46) | FAAHMAPT | |
| SCHEMBL1706068 | 0.82 | MAPT (0.41) | FAAHMAPT | |
| SCHEMBL6867730 | 0.80 | MAPT (0.41) | FAAHMAPT | |
| SCHEMBL7716571 | 0.77 | FAAH (0.42) | FAAHMAPT | |
| SCHEMBL4246694 | 0.77 | FAAH (0.42) | FAAHMAPT | |
| SCHEMBL1445320 | 0.77 | MAPT (0.40) | FAAHMAPT | |
| SCHEMBL7614587 | 0.77 | MAPT (0.40) | FAAHMAPT | |
| SCHEMBL9683369 | 0.75 | FAAH (0.41) | FAAHMAPT | |
| SCHEMBL334795 | 0.75 | MAPT (0.44) | FAAHMAPT | |
| SCHEMBL11454859 | 0.75 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613775-B1 | 8-(2,6-dimethylbenzylamino)-2-hydroxymethyl-3-methylimidazo(1, 2-a)pyridine used as antisecretory agents for prophylaxis of gastrointestinal disorders such as ulcers | ASTRAZENECA AB (SE) | 2003-09-02 | — | — | US | disclosed |
| EP-1105390-B1 | Imidazo[1,2-a]pyridine derivatives for the treatment of gastrointestinal diseases | ASTRAZENECA AB (SE) | 2003-06-04 | — | — | EP | disclosed |
| EP-1105390-A2 | NEW COMPOUNDS | AstraZeneca AB (SE) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000010999-A2 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 2000-03-02 | — | — | WO | disclosed |