Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18351089 | 0.85 | ALDH1A1 (0.57) | ALDH1A1KDM4EGAARXFP1HPGD | |
| SCHEMBL7007577 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAARXFP1HPGD | |
| SCHEMBL18351095 | 0.82 | MAPK1 (0.58) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL14875795 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAARXFP1HPGD | |
| SCHEMBL3492144 | 0.81 | ALDH1A1 (0.65) | ALDH1A1KDM4EGAARXFP1HPGD | |
| SCHEMBL14875871 | 0.79 | TYMS (0.60) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL4506134 | 0.77 | KDM4E (0.57) | ALDH1A1KDM4EGAARXFP1HPGD | |
| SCHEMBL7016922 | 0.77 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL7017750 | 0.76 | ALDH1A1 (0.60) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL5123831 | 0.74 | ALDH1A1 (0.72) | ALDH1A1KDM4EGAARXFP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329454-A1 | THIENOPYRIMIDINE COMPOUNDS AND THEIR SALTS AND PROCESS FOR PREPARATION OF BOTH | NIPPON SODA CO., LTD. (JP) | 2003-07-23 | — | — | EP | disclosed |