Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007582 | 0.82 | ALDH1A1 (0.65) | ALDH1A1KDM4EKMT2AMAPTKDM4C | |
| SCHEMBL7018701 | 0.76 | CDC7 (0.51) | ALDH1A1KDM4EKMT2AMAPTGAA | |
| SCHEMBL19002531 | 0.75 | HTT (0.56) | ALDH1A1KDM4EKMT2AMAPTHPGD | |
| SCHEMBL7017749 | 0.74 | CDC7 (0.46) | ALDH1A1KDM4EKMT2AMAPTHPGD | |
| SCHEMBL18351089 | 0.72 | ALDH1A1 (0.57) | ALDH1A1KDM4EKMT2AMAPTKDM4C | |
| SCHEMBL14885247 | 0.71 | XDH (0.48) | ALDH1A1KDM4EHPGD | |
| SCHEMBL7016922 | 0.69 | ALDH1A1 (0.62) | ALDH1A1KDM4EKMT2AMAPTHPGD | |
| SCHEMBL5129176 | 0.69 | CYP2C19 (0.42) | ALDH1A1KDM4E | |
| SCHEMBL18351095 | 0.68 | MAPK1 (0.58) | ALDH1A1KDM4EKMT2AMAPTHPGD | |
| SCHEMBL4395277 | 0.68 | ALDH1A1 (0.55) | ALDH1A1KDM4EKMT2AMAPTKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329454-A1 | THIENOPYRIMIDINE COMPOUNDS AND THEIR SALTS AND PROCESS FOR PREPARATION OF BOTH | NIPPON SODA CO., LTD. (JP) | 2003-07-23 | — | — | EP | disclosed |