Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007615 | 1.00 | PABPC1 (0.44) | PABPC1NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL5183226 | 0.86 | ALDH1A1 (0.42) | PABPC1NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL5183228 | 0.86 | ALDH1A1 (0.42) | PABPC1NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL5427351 | 0.85 | JAK3 (0.44) | PABPC1NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL5168964 | 0.85 | JAK3 (0.44) | PABPC1NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL5432246 | 0.85 | NPC1 (0.43) | PABPC1NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL5172633 | 0.85 | NPC1 (0.43) | PABPC1NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL5460602 | 0.84 | HTT (0.46) | PABPC1NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL5196258 | 0.84 | HTT (0.46) | PABPC1NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL7013827 | 0.80 | ALDH1A1 (0.42) | NPC1RAB9AALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1180105-B1 | SUBSTITUTED AZA-OXINDOLE DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-05-14 | — | — | EP | claimed |