SCHEMBL7007875

SCHEMBL7007875

CN(C)c1ccc(C2(c3ccc(N(C)C)cc3N(C)C)OC(=O)c3ccccc32)c(N(C)C)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.59
CYP3A4 P08684 4/20 0.59
ALDH1A1 P00352 4/20 0.59
HPGD P15428 2/20 0.59
HSD17B10 Q99714 2/20 0.59
HIF1A Q16665 2/20 0.59
MEN1 O00255 7/20 0.51
KMT2A Q03164 7/20 0.51
MAPT P10636 6/20 0.51
LMNA P02545 6/20 0.51
NPSR1 Q6W5P4 4/20 0.51
POLB P06746 3/20 0.51
FTO Q9C0B1 2/20 0.51
HTT P42858 2/20 0.51
GPR55 Q9Y2T6 2/20 0.51
CYP2C19 P33261 2/20 0.51
RECQL P46063 2/20 0.51
BLM P54132 2/20 0.51
PRMT1 Q99873 2/20 0.51
ACE2 Q9BYF1 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10935899 0.92 TDP1 (0.69) TDP1CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL2905368 0.89 ALDH1A1 (0.68) TDP1CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL11438894 0.86 MAPT (0.51) TDP1CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL11429012 0.86 TDP1 (0.46) TDP1CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL9610878 0.86 FTO (0.66) TDP1CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL31580046 0.86 FTO (0.66) TDP1CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL11259358 0.86 TDP1 (0.48) TDP1CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL11439609 0.85 MEN1 (0.72) TDP1CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL253481 0.85 CFTR (0.56) TDP1CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL21575564 0.84 TDP1 (0.58) TDP1CYP3A4ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030139293-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2003-07-24 US claimed
EP-1268215-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2003-01-02 EP claimed
WO-2001072527-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-10-04 WO claimed
US-20030139293-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2003-07-24 US disclosed
EP-1268215-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2003-01-02 EP disclosed
WO-2001072527-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-10-04 WO disclosed
US-4643588-A COATED CARRIER OF A GELATIN LAYER CONTAINING AN ACIDIC REACTANT, COLOR FORMER AND AN ENCAPSULATED NON-AQUEOUS SOLVENT CIBA-GEIGY AG (CH) 1987-02-17 US disclosed
EP-0159965-A2 Method of monitoring temperatureand device for carrying out said method ILFORD Limited (GB) 1985-10-30 EP disclosed
US-4096176-A Benzoylbenzoic acids STERLING DRUG INC. (US) 1978-06-20 US disclosed