SCHEMBL7008701

SCHEMBL7008701

SCCc1cccc(Br)c1

nearest known ligand 0.63

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.63
IDO1 P14902 2/20 0.50
AGXT P21549 2/20 0.50
MAOB P27338 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
SIGMAR1 Q99720 1/20 0.41
GPR84 Q9NQS5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4399626 0.85 TAAR1 (0.74) TAAR1IDO1AGXTMAOBSMN1; SMN2
SCHEMBL332301 0.83 MEN1 (0.48) TAAR1IDO1MAOB
SCHEMBL5240585 0.81 TAAR1 (0.68) TAAR1IDO1AGXTMAOBSMN1; SMN2
SCHEMBL7369600 0.81
SCHEMBL19524669 0.79 TAAR1 (0.65) TAAR1IDO1AGXTMAOBSMN1; SMN2
SCHEMBL705920 0.79 TAAR1 (0.65) TAAR1IDO1AGXTMAOBSMN1; SMN2
SCHEMBL30688447 0.79 TAAR1 (0.65) TAAR1IDO1AGXTMAOBSMN1; SMN2
SCHEMBL9660784 0.79 TAAR1 (0.65) TAAR1IDO1AGXTMAOBTDP1
SCHEMBL1042388 0.78 TAAR1 (0.59) TAAR1IDO1AGXTMAOBSMN1; SMN2
SCHEMBL1646500 0.77 TAAR1 (0.63) TAAR1IDO1AGXTMAOBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100069603-A1 METHOD FOR PRODUCING STRUCTURE WHEREIN AROMATIC POLYMER IS BONDED TO BASE, STRUCTURE HAVING AROMATIC POLYMER CHAIN BONDED TO CONDUCTIVE BASE, AND ELECTRONIC DEVICE COMPRISING THE STRUCTURE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-18 US disclosed
US-20100069603-A1 METHOD FOR PRODUCING STRUCTURE WHEREIN AROMATIC POLYMER IS BONDED TO BASE, STRUCTURE HAVING AROMATIC POLYMER CHAIN BONDED TO CONDUCTIVE BASE, AND ELECTRONIC DEVICE COMPRISING THE STRUCTURE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-18 US disclosed
EP-2110398-A1 METHOD FOR PRODUCING STRUCTURE WHEREIN AROMATIC POLYMER IS BONDED TO BASE, STRUCTURE HAVING AROMATIC POLYMER CHAIN BONDED TO CONDUCTIVE BASE, AND ELECTRONIC DEVICE COMPRISING THE STRUCTURE Sumitomo Chemical Company, Limited (JP) 2009-10-21 EP disclosed
EP-1054857-B1 BIARYL-ACETIC ACID DERIVATIVES AND THEIR USE AS COX-2 INHIBITORS MERCK FROSST CANADA INC (CA) 2003-11-05 EP disclosed
US-5994379-A Bisaryl COX-2 inhibiting compounds, compositions and methods of use MERCK FROSST CANADA, INC. (CA) 1999-11-30 US disclosed