Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.56 |
| ▸ | HTR2C | P28335 | 9/20 | 0.40 |
| ▸ | HTR2A | P28223 | 7/20 | 0.40 |
| ▸ | HTR2B | P41595 | 7/20 | 0.40 |
| ▸ | HTR1A | P08908 | 6/20 | 0.40 |
| ▸ | HTR1D | P28221 | 5/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyanide SCHEMBL27496770 | 0.96 | MTNR1A (0.53) | MTNR1AHTR2CHTR2AHTR2BHTR1A | |
| SCHEMBL8169091 | 0.80 | MTNR1A (0.63) | MTNR1AHTR2CHTR2AHTR2BHTR1A | |
| SCHEMBL7238794 | 0.79 | MTNR1A (0.49) | MTNR1AHTR2CHTR2AHTR2BHTR1A | |
| SCHEMBL7238217 | 0.78 | MTNR1A (0.56) | MTNR1AHTR2CHTR2AHTR2BHTR1A | |
| Hydrochloric Acid SCHEMBL8169452 | 0.78 | MTNR1A (0.62) | MTNR1AHTR2CHTR2AHTR2BHTR1A | |
| SCHEMBL7007789 | 0.78 | MTNR1A (0.59) | MTNR1AHTR2CHTR2AHTR2BHTR1A | |
| SCHEMBL7016214 | 0.76 | MTNR1A (0.47) | MTNR1AHTR2CHTR2AHTR2BHTR1A | |
| SCHEMBL7011796 | 0.76 | MTNR1A (0.59) | MTNR1AHTR2CHTR2AHTR2BHTR1A | |
| Ammonia Solution, Strong SCHEMBL27497763 | 0.75 | MTNR1A (0.46) | MTNR1AHTR2CHTR2AHTR2BHTR1A | |
| SCHEMBL8169871 | 0.74 | MTNR1A (0.75) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994102-B1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | disclosed |
| EP-0994102-A1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-04-19 | — | — | EP | disclosed |