Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.59 |
| ▸ | HTR2C | P28335 | 9/20 | 0.40 |
| ▸ | HTR2A | P28223 | 7/20 | 0.40 |
| ▸ | HTR2B | P41595 | 7/20 | 0.40 |
| ▸ | HTR1A | P08908 | 6/20 | 0.40 |
| ▸ | HTR1D | P28221 | 5/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169091 | 0.80 | MTNR1A (0.63) | MTNR1AHTR2CHTR2AHTR2BHTR1A | |
| Hydrochloric Acid SCHEMBL8169452 | 0.78 | MTNR1A (0.62) | MTNR1AHTR2CHTR2AHTR2BHTR1A | |
| SCHEMBL7008905 | 0.78 | MTNR1A (0.56) | MTNR1AHTR2CHTR2AHTR2BHTR1A | |
| Cyanide SCHEMBL27496770 | 0.75 | MTNR1A (0.53) | MTNR1AHTR2CHTR2AHTR2BHTR1A | |
| SCHEMBL7797256 | 0.74 | MTNR1A (1.00) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8162670 | 0.74 | MTNR1A (0.75) | MTNR1AHTR2CHTR2AHTR2BHTR1A | |
| SCHEMBL8170080 | 0.73 | MTNR1A (0.78) | MTNR1AHTR2CHTR2AHTR2BHTR1A | |
| SCHEMBL8400893 | 0.73 | MTNR1A (0.68) | MTNR1AHTR2CHTR2AHTR2BHTR1A | |
| SCHEMBL7238217 | 0.73 | MTNR1A (0.56) | MTNR1AHTR2CHTR2AHTR2BHTR1A | |
| SCHEMBL8175004 | 0.73 | MTNR1A (0.76) | MTNR1AHTR2CHTR2AHTR2BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1216856-C | Novel cyclocompound having cycloalkylene chain, prepn. method and pharmaceutical compositions contg. same | ADIR (FR) | 2005-08-31 | — | — | CN | disclosed |
| US-6583319-B1 | Treating or preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-06-24 | — | — | US | disclosed |
| EP-0994102-B1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | disclosed |
| EP-0994102-A1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-04-19 | — | — | EP | disclosed |