SCHEMBL700910

SCHEMBL700910

O=Cc1ccc(O)c2ncccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 1.00
L3MBTL1 Q9Y468 5/20 1.00
HSP90AA1 P07900 4/20 1.00
NPC1 O15118 4/20 1.00
RAB9A P51151 4/20 1.00
IDO1 P14902 2/20 1.00
NPSR1 Q6W5P4 2/20 1.00
MEN1 O00255 1/20 1.00
KMT2A Q03164 1/20 1.00
APP P05067 1/20 0.60
ERN1 O75460 1/20 0.60
MAPT P10636 3/20 0.56
LMNA P02545 3/20 0.56
HTT P42858 3/20 0.56
BRD4 O60885 2/20 0.56
METAP2 P50579 2/20 0.56
MPI P34949 1/20 0.56
METAP1 P53582 1/20 0.56
HSP90AB1 P08238 1/20 0.56
PSMB5 P28074 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30080768 1.00 KDM4E (1.00) KDM4EL3MBTL1HSP90AA1NPC1RAB9A
SCHEMBL21625616 0.86 KDM4E (0.75) KDM4EL3MBTL1HSP90AA1NPC1RAB9A
SCHEMBL29950806 0.86 KDM4E (0.75) KDM4EL3MBTL1HSP90AA1NPC1RAB9A
SCHEMBL28428092 0.83 KDM4E (0.71) KDM4EL3MBTL1HSP90AA1NPC1RAB9A
Formamide SCHEMBL9731471 0.82 KDM4E (0.69) KDM4EL3MBTL1HSP90AA1NPC1RAB9A
SCHEMBL7258719 0.82 KDM4E (0.70) KDM4EL3MBTL1HSP90AA1NPC1RAB9A
SCHEMBL28677018 0.81 KDM4E (0.68) KDM4EL3MBTL1HSP90AA1NPC1RAB9A
SCHEMBL28200686 0.81 KDM4E (0.68) KDM4EL3MBTL1HSP90AA1NPC1RAB9A
SCHEMBL9731468 0.80 KDM4E (0.66) KDM4EL3MBTL1HSP90AA1NPC1RAB9A
SCHEMBL30521953 0.79 KDM4E (0.67) KDM4EL3MBTL1HSP90AA1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12249691-B2 Electrolyte-solution composition and secondary battery using same ADVANCED LITHIUM ELECTROCHEMISTRY CO., LTD. (TW) 2025-03-11 US claimed
CN-119504732-A Near infrared RNA selective fluorescent probe, preparation method and application for tracking stress particle dynamics in living cells 安庆师范大学 2025-02-25 CN claimed
CN-117264476-A PTFE non-stick coating 慈溪市中一涂料有限公司 2023-12-22 CN claimed
CN-117138757-A S-SBA-15 adsorbent and preparation method and application thereof 淮阴师范学院 2023-12-01 CN claimed
CN-112250843-B Four kinds of D-A' - (pi-A) 2 Polymeric alkylated salicylaldehyde Schiff base derivative metal complex and preparation method and application thereof 湘潭大学 2023-05-30 CN claimed
CN-114805763-B Three copolymer complexes with benzodithiophene derivatives as ligands, and preparation method and application thereof 湘潭大学 2023-05-26 CN claimed
CN-113321670-B Four kinds of D-A' - (pi-A) 2 Polymeric alkylated pyridine derivative metal complex and preparation method and application thereof 湘潭大学 2023-05-26 CN claimed
CN-113354666-B Four kinds of D-A' - (pi-A) 2 Metal complex of polymeric salicylaldehyde Schiff base derivative, preparation method and application thereof 湘潭大学 2023-05-26 CN claimed
CN-112225883-B Four kinds of D-A' - (pi-A) 2 Metal complex of polymeric pyridine derivative and preparation method and application thereof 湘潭大学 2023-05-26 CN claimed
CN-112279870-B Dye sensitizer of imine derivative and 8-hydroxyquinoline derivative cadmium complex, and preparation method and application thereof 湘潭大学 2023-05-23 CN claimed
CN-102887915-B Heteronuclear bimetallic complex light-emitting material and preparation method and application thereof UNIV JIAYING 2014-12-31 CN claimed
CN-103320121-A Organic/inorganic hybrid fluorescent powder, preparation method thereof, and application of organic/inorganic hybrid fluorescent powder to white light light-emitting diode (LED) light source UNIV FUJIAN 2013-09-25 CN claimed
CN-102887915-A Heteronuclear bimetallic complex light-emitting material and preparation method and application thereof UNIV JIAYING 2013-01-23 CN claimed
WO-2009140215-A2 METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS GERAGHTY, ERIN (US) 2009-11-19 WO claimed
US-20080207673-A1 Method for Treating Cancer, Coronary, Inflammatory and Macular Disease, Combining the Modulation of Zinc-and/or Copper Dependent Proteins XILINAS MICHEL 2008-08-28 US claimed
EP-1189606-B1 NOVEL IRON CHELATORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING IRON CHELATORS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS YEDA RES & DEV (IL) 2007-08-15 EP claimed
US-6855711-B1 Pharmaceutical compositions comprising iron chelators for the treatment of neurodegenerative disorders and some novel iron chelators YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2005-02-15 US claimed
EP-1189606-A2 NOVEL IRON CHELATORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING IRON CHELATORS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS YEDA RESEARCH AND DEVELOPMENT Co. LTD. (IL) 2002-03-27 EP claimed
WO-2000074664-A2 NOVEL IRON CHELATORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING IRON CHELATORS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2000-12-14 WO claimed
US-4714614-A PSEUDOMONAS AND FERRIC ION CHELATING AGENT COLORADO STATE UNIVERSITY (US) 1987-12-22 US claimed