SCHEMBL28200686

SCHEMBL28200686

C=Cc1ccc(O)c2ncccc12.[AlH3]

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.68
L3MBTL1 Q9Y468 5/20 0.68
HSP90AA1 P07900 4/20 0.68
NPC1 O15118 4/20 0.68
RAB9A P51151 4/20 0.68
IDO1 P14902 2/20 0.68
NPSR1 Q6W5P4 2/20 0.68
MEN1 O00255 1/20 0.68
KMT2A Q03164 1/20 0.68
APP P05067 1/20 0.59
LMNA P02545 3/20 0.54
HTT P42858 3/20 0.54
MAPT P10636 3/20 0.54
BRD4 O60885 2/20 0.54
METAP2 P50579 2/20 0.54
MPI P34949 1/20 0.54
METAP1 P53582 1/20 0.54
HSP90AB1 P08238 1/20 0.54
PSMB5 P28074 1/20 0.54
SLC6A2 P23975 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7258719 0.98 KDM4E (0.70) KDM4EL3MBTL1HSP90AA1NPC1RAB9A
SCHEMBL28677018 0.97 KDM4E (0.68) KDM4EL3MBTL1HSP90AA1NPC1RAB9A
Formamide SCHEMBL9731471 0.91 KDM4E (0.69) KDM4EL3MBTL1HSP90AA1NPC1RAB9A
SCHEMBL700910 0.81 KDM4E (1.00) KDM4EL3MBTL1HSP90AA1NPC1RAB9A
SCHEMBL30080768 0.81 KDM4E (1.00) KDM4EL3MBTL1HSP90AA1NPC1RAB9A
SCHEMBL27816447 0.79 KDM4E (0.68) KDM4EL3MBTL1HSP90AA1NPC1RAB9A
SCHEMBL28201239 0.78 KDM4E (0.97) KDM4EL3MBTL1HSP90AA1NPC1RAB9A
Formamide SCHEMBL9731188 0.78 KDM4E (0.56) KDM4EL3MBTL1HSP90AA1NPC1RAB9A
Formamide SCHEMBL9730893 0.78 KDM4E (0.53) KDM4EL3MBTL1HSP90AA1NPC1RAB9A
SCHEMBL1920452 0.77 KDM4E (0.70) KDM4EL3MBTL1HSP90AA1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107721921-A A kind of new 8 hydroxyquinoline aluminum green light material of Wavelength tunable and preparation method thereof 广州工程技术职业学院 2018-02-23 CN claimed
CN-107721921-A A kind of new 8 hydroxyquinoline aluminum green light material of Wavelength tunable and preparation method thereof 广州工程技术职业学院 2018-02-23 CN disclosed