Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7009366 | 0.85 | GRM2 (0.35) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL7007914 | 0.81 | GRM2 (0.37) | NPC1RAB9AALDH1A1CYP2C9GAA | |
| SCHEMBL7011855 | 0.80 | HSD17B10 (0.43) | ALDH1A1KMT2AL3MBTL1HPGDHSD17B10 | |
| SCHEMBL7007419 | 0.77 | GRM2 (0.33) | — | |
| SCHEMBL7009338 | 0.76 | CYP1A2 (0.43) | SMN1; SMN2ALDH1A1CYP2C9KDM4EHTT | |
| SCHEMBL9054906 | 0.76 | MAPT (0.37) | SMN1; SMN2NPC1RAB9AALDH1A1CYP2C9 | |
| SCHEMBL7007029 | 0.73 | NPC1 (0.36) | TP53NPC1RAB9AALDH1A1GAA | |
| SCHEMBL15669005 | 0.71 | SMN1; SMN2 (0.67) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL2341793 | 0.70 | SMN1; SMN2 (0.65) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL7012334 | 0.70 | GRM2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772593-B1 | THIOPYRIDYL COMPOUNDS FOR CONTROLLING HELICOBACTER BACTERIA | ALTANA PHARMA AG (DE) | 2003-05-02 | — | — | EP | disclosed |
| US-6162809-A | Pyridylthio compounds for controlling helicobacter bacteria | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-12-19 | — | — | US | disclosed |