Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7009360 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2TP53L3MBTL1NPC1RAB9A | |
| SCHEMBL7007914 | 0.79 | GRM2 (0.37) | GRM2PKMNPC1RAB9AALDH1A1 | |
| SCHEMBL7011855 | 0.76 | HSD17B10 (0.43) | GRM2PKML3MBTL1ALDH1A1 | |
| SCHEMBL7007419 | 0.74 | GRM2 (0.33) | GRM2PKM | |
| SCHEMBL7009338 | 0.74 | CYP1A2 (0.43) | GRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL9054906 | 0.73 | MAPT (0.37) | GRM2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7007029 | 0.71 | NPC1 (0.36) | GRM2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL7012334 | 0.68 | GRM2 (0.31) | GRM2 | |
| SCHEMBL7007309 | 0.68 | NPC1 (0.52) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL7011246 | 0.68 | ALDH1A1 (0.46) | SMN1; SMN2TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772593-B1 | THIOPYRIDYL COMPOUNDS FOR CONTROLLING HELICOBACTER BACTERIA | ALTANA PHARMA AG (DE) | 2003-05-02 | — | — | EP | disclosed |