⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL587459 | 0.80 | — | — | |
| SCHEMBL31261225 | 0.78 | — | — | |
| SCHEMBL23401592 | 0.77 | POLB (0.40) | — | |
| SCHEMBL23136478 | 0.75 | PRKCE (0.33) | — | |
| SCHEMBL23400805 | 0.75 | GABRA1 (0.36) | — | |
| SCHEMBL23403442 | 0.74 | NPC1 (0.37) | — | |
| SCHEMBL22345987 | 0.72 | KDM4E (0.51) | — | |
| SCHEMBL22952626 | 0.71 | HDAC1 (0.38) | — | |
| SCHEMBL11374566 | 0.70 | — | — | |
| SCHEMBL11649094 | 0.70 | TYR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1135227-C | 2,6-twice substituted pyridine and 2,4-twice substituted pyrimidine for berbicide | 谷 | 2004-01-21 | — | — | CN | disclosed |
| CN-1117748-C | Herbicidal 2, 6 -disubstituted pyridines and 2, 4 -disubstituted pyrimidines | AMERICAN CYANAMID CO (US) | 2003-08-13 | — | — | CN | disclosed |
| EP-0723960-B1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | BASF AG (DE) | 2003-04-02 | — | — | EP | disclosed |
| US-6066597-A | Herbicidal 2-(hetero)aryloxy-6-arylpyridines and 2-aryl-4-(hetero)aryloxy-6-arylpyridines and 2-aryl-4-(hetero)aryloxypyrimidines | AMERICAN CYANAMID COMPANY (US) | 2000-05-23 | — | — | US | disclosed |
| US-6008161-A | Herbicidal 2-(hetero)aryloxy-6-arylpyridines and 2-aryl-4-(hetero) aryloxypyrimidines | AMERICAN CYANAMID COMPANY (US) | 1999-12-28 | — | — | US | disclosed |
| US-5849758-A | Herbicidal 2, 6-disubstituted pyridines and 2, 4-disubstituted pyrimidines | AMERICAN CYANAMID COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| US-5824624-A | HERBICIDES WITH CARRIERS OR SURFACTANTS | AMERICAN CYANAMID COMPANY (US) | 1998-10-20 | — | — | US | disclosed |
| CN-1175578-A | Herbicidal 2, 6 -disubstituted pyridines and 2, 4 -disubstituted pyrimidines | AMERICAN CYANAMID CO (US) | 1998-03-11 | — | — | CN | disclosed |
| EP-0823431-A1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | American Cyanamid Company (US) | 1998-02-11 | — | — | EP | disclosed |
| CN-1143078-A | 2,6-twice substituted pyridine and 2,4-twice substituted pyrimidine for berbicide | AMERICAN CYANAMID CO (US) | 1997-02-19 | — | — | CN | disclosed |
| EP-0723960-A1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | American Cyanamid Company (US) | 1996-07-31 | — | — | EP | disclosed |