Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CTSK | P43235 | 3/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2679161 | 0.89 | ATM (0.64) | ATMALDH1A1CTSKCTSLCTSS | |
| SCHEMBL9828589 | 0.88 | ATM (0.63) | ATMALDH1A1CTSKCTSLCTSS | |
| SCHEMBL9828584 | 0.88 | ATM (0.63) | ATMALDH1A1CTSKCTSLCTSS | |
| SCHEMBL11813827 | 0.86 | CTSK (0.64) | ATMALDH1A1CTSKCTSLCTSS | |
| SCHEMBL319160 | 0.85 | CTSK (0.64) | ALDH1A1CTSKCTSLCTSSPPARG | |
| SCHEMBL2895983 | 0.85 | CTSK (0.64) | ALDH1A1CTSKCTSLCTSSPPARG | |
| SCHEMBL265512 | 0.85 | CTSK (0.64) | ALDH1A1CTSKCTSLCTSSPPARG | |
| SCHEMBL7044299 | 0.85 | ATM (0.67) | ATMALDH1A1CTSKCTSLCTSS | |
| SCHEMBL9716776 | 0.85 | ATM (0.67) | ATMALDH1A1CTSKCTSLCTSS | |
| SCHEMBL7039089 | 0.85 | ATM (0.67) | ATMALDH1A1CTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285671-B1 | PYRIDINE DERIVATIVES | ASAHI CHEMICAL IND (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-5126448-A | Anxiolytic agents, learning enhancement | ASAHI KASEI KOGYO K.K. (JP) | 1992-06-30 | — | — | US | disclosed |
| EP-0285671-A1 | PYRIDINE DERIVATIVES | Asahi Kasei Kabushiki Kaisha (JP) | 1988-10-12 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |