Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.67 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.67 |
| ▸ | FPR2 | P25090 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.63 |
| ▸ | CTSL | P07711 | 2/20 | 0.62 |
| ▸ | CTSS | P25774 | 2/20 | 0.62 |
| ▸ | CTSK | P43235 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | F2 | P00734 | 1/20 | 0.60 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.59 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.59 |
| ▸ | CTSB | P07858 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7039089 | 1.00 | ATM (0.67) | ATMITGB3ITGA2BFPR2KMT2A | |
| SCHEMBL7044299 | 1.00 | ATM (0.67) | ATMITGB3ITGA2BFPR2KMT2A | |
| SCHEMBL7044293 | 1.00 | ATM (0.67) | ATMITGB3ITGA2BFPR2KMT2A | |
| SCHEMBL9716778 | 1.00 | ATM (0.67) | ATMITGB3ITGA2BFPR2KMT2A | |
| SCHEMBL7317573 | 0.95 | HDAC8 (0.64) | ATMITGB3ITGA2BFPR2HDAC8 | |
| SCHEMBL14684392 | 0.95 | HDAC8 (0.64) | ATMITGB3ITGA2BFPR2HDAC8 | |
| SCHEMBL8569421 | 0.92 | ALDH1A1 (0.65) | ATMITGB3ITGA2BKMT2AHDAC8 | |
| SCHEMBL10706226 | 0.92 | ATM (0.60) | ATMITGB3ITGA2BFPR2KMT2A | |
| SCHEMBL2406036 | 0.92 | ALDH1A1 (0.65) | ATMITGB3ITGA2BKMT2AHDAC8 | |
| SCHEMBL11059108 | 0.91 | CTSL (0.60) | ATMITGB3ITGA2BFPR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| EP-0156279-B1 | A NOVEL PROCESS FOR THE PREPARATION OF BESTATIN DERIVATIVES AND INTERMEDIATES THEREOF | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1989-09-13 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |
| EP-0156279-A2 | A novel process for the preparation of bestatin derivatives and intermediates thereof | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1985-10-02 | — | — | EP | disclosed |