Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | OGFRL1 | Q5TC84 | 12/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | PRKACA | P17612 | 2/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5108137 | 0.80 | L3MBTL1 (0.65) | L3MBTL1 | |
| SCHEMBL14382628 | 0.79 | L3MBTL1 (0.63) | L3MBTL1 | |
| SCHEMBL791584 | 0.75 | CYP1A2 (0.47) | L3MBTL1 | |
| SCHEMBL28236159 | 0.75 | CYP11B2 (0.63) | OGFRL1OPRM1OPRK1OPRD1HDAC1 | |
| SCHEMBL14382557 | 0.74 | L3MBTL1 (0.59) | L3MBTL1OGFRL1HDAC1HDAC6RPS6KB1 | |
| Hydrochloric Acid SCHEMBL7175207 | 0.74 | RPS6KB1 (0.56) | OGFRL1OPRM1OPRK1OPRD1HDAC1 | |
| Hydrochloric Acid SCHEMBL7182759 | 0.74 | RPS6KB1 (0.56) | OGFRL1OPRM1OPRK1OPRD1HDAC1 | |
| Hydrochloric Acid SCHEMBL7183988 | 0.74 | RPS6KB1 (0.56) | OGFRL1OPRM1OPRK1OPRD1HDAC1 | |
| Hydrochloric Acid SCHEMBL7185555 | 0.74 | RPS6KB1 (0.56) | OGFRL1OPRM1OPRK1OPRD1HDAC1 | |
| Hydrochloric Acid SCHEMBL7175623 | 0.74 | RPS6KB1 (0.56) | OGFRL1OPRM1OPRK1OPRD1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301487-A2 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002004425-A2 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2002-01-17 | — | — | WO | disclosed |